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Enrico Smeraldi Selected Research

Sleep Deprivation

1/2016Stem Cell Factor (SCF) is a putative biomarker of antidepressant response.
8/2015Successful antidepressant chronotherapeutics enhance fronto-limbic neural responses and connectivity in bipolar depression.
3/2015Disruption of white matter integrity marks poor antidepressant response in bipolar disorder.
12/2014Changes of cortical excitability as markers of antidepressant response in bipolar depression: preliminary data obtained by combining transcranial magnetic stimulation (TMS) and electroencephalography (EEG).
2/2012Gene-gene interaction of glycogen synthase kinase 3-β and serotonin transporter on human antidepressant response to sleep deprivation.
2/2010Acute antidepressant response to sleep deprivation combined with light therapy is influenced by the catechol-O-methyltransferase Val(108/158)Met polymorphism.
9/2009Spectroscopic correlates of antidepressant response to sleep deprivation and light therapy: a 3.0 Tesla study of bipolar depression.
1/2009Neuroimaging and genetics of antidepressant response to sleep deprivation: implications for drug development.
12/2008Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression.
4/2008Lithium overcomes the influence of 5-HTTLPR gene polymorphism on antidepressant response to sleep deprivation.
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Enrico Smeraldi Research Topics

Disease

31Bipolar Disorder (Manic Depressive Psychosis)
01/2016 - 06/2003
24Mood Disorders (Mood Disorder)
06/2010 - 02/2002
20Sleep Deprivation
01/2016 - 10/2002
19Schizophrenia (Dementia Praecox)
01/2016 - 05/2007
10Major Depressive Disorder (Major Depressive Disorders)
12/2013 - 04/2003
4Mania (Manias)
12/2013 - 02/2005
3Cognitive Dysfunction
01/2016 - 08/2012
3Sleep Initiation and Maintenance Disorders (Insomnia)
04/2014 - 09/2004
3Psychotic Disorders (Schizoaffective Disorder)
08/2013 - 09/2004
3Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
07/2013 - 01/2009
2Depressive Disorder (Melancholia)
05/2012 - 12/2007
2Hyperprolactinemia
11/2010 - 02/2004
2Sleepiness
11/2010 - 09/2004
2Migraine Disorders (Migraine)
06/2010 - 08/2004
1Treatment-Resistant Schizophrenia
01/2015
1Demyelinating Diseases (Demyelinating Disease)
08/2012
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
12/2010
1Alzheimer Disease (Alzheimer's Disease)
12/2010
1Dementia (Dementias)
12/2010
1Weight Gain
11/2010
1Personality Disorders (Personality Disorder)
03/2007
1Hypersensitivity (Allergy)
11/2004
1Myocarditis (Carditis)
11/2004
1Disorders of Excessive Somnolence (Hypersomnia)
09/2004
1Multiple Sclerosis
01/2004
1Wolfram Syndrome (Syndrome, Wolfram)
06/2003

Drug/Important Bio-Agent (IBA)

31Antidepressive Agents (Antidepressants)IBA
01/2016 - 10/2002
14Pharmaceutical PreparationsIBA
07/2013 - 10/2002
9LithiumIBA
04/2015 - 05/2002
9Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
02/2015 - 05/2002
9Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
12/2014 - 02/2002
8Biological ProductsIBA
01/2016 - 11/2002
7Antipsychotic Agents (Antipsychotics)IBA
01/2015 - 11/2004
5Dopamine (Intropin)FDA LinkGeneric
02/2015 - 01/2007
5Risperidone (Risperdal Consta)FDA LinkGeneric
08/2013 - 02/2004
4Clozapine (Clozaril)FDA LinkGeneric
01/2015 - 09/2004
4Serotonin (5 Hydroxytryptamine)IBA
02/2010 - 08/2005
4Glycogen Synthase KinasesIBA
03/2008 - 01/2004
3SaltsIBA
03/2008 - 08/2004
3Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
09/2007 - 08/2004
3Dopamine Receptors (Dopamine Receptor)IBA
06/2003 - 05/2002
3Monoamine Oxidase (MAO)IBA
05/2002 - 05/2002
2ElementsIBA
01/2015 - 02/2013
2agomelatine (S20098)IBA
11/2013 - 02/2010
2Olanzapine (Zyprexa)FDA Link
08/2013 - 11/2010
2Quetiapine Fumarate (Seroquel)FDA Link
08/2013 - 11/2010
2Glycogen Synthase Kinase 3IBA
01/2013 - 02/2012
2Glutamic Acid (Glutamate)FDA Link
08/2012 - 09/2009
2Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
05/2012 - 12/2005
2Sertraline (Zoloft)FDA LinkGeneric
02/2010 - 12/2005
2Neurotransmitter Agents (Neurotransmitter)IBA
09/2009 - 06/2003
2Paroxetine (Paxil)FDA LinkGeneric
03/2009 - 04/2003
25-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
12/2008 - 04/2003
2Fluvoxamine (Luvox)FDA LinkGeneric
08/2006 - 01/2004
1Becaplermin (PDGF-BB)FDA Link
01/2016
1Stem Cell FactorIBA
01/2016
1Insulin-Like Growth Factor Binding Protein 2IBA
01/2016
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2016
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2016
1Calcium-Binding ProteinsIBA
01/2016
1Epidermal Growth Factor (EGF)IBA
01/2016
1Glycogen Synthase (Synthase I)IBA
04/2015
1Biomarkers (Surrogate Marker)IBA
03/2015
1SterolsIBA
01/2015
1Transcription Factors (Transcription Factor)IBA
01/2015
1Amino Acid Transport System X-AG (Glutamate Transporter)IBA
06/2014
1Excitatory Amino AcidsIBA
05/2014
1Paliperidone PalmitateFDA Link
04/2014
1acceleratory factor from growth hormone (AcG)IBA
01/2013
1ovomucoid inhibitors (TOMI)IBA
01/2013
1metabotropic glutamate receptor 3 (mGluR3)IBA
08/2012
15-HT1A Serotonin ReceptorIBA
07/2011
1methionylmethionine (Met-Met)IBA
07/2011
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
12/2010
1tau Proteins (tau Protein)IBA
12/2010
1ProlactinIBA
11/2010
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
02/2010
1EnzymesIBA
03/2008
1Glycogen Synthase Kinase 3 betaIBA
03/2008
1Aripiprazole (Abilify)FDA Link
10/2007
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2007
1EscitalopramFDA Link
12/2005
1Adrenal Cortex Hormones (Corticosteroids)IBA
11/2004
1lormetazepamIBA
09/2004
1BenzodiazepinesIBA
09/2004
1CabergolineFDA LinkGeneric
02/2004
1Interferon beta-1b (Betaseron)FDA Link
01/2004
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
09/2003
1Dopamine D3 ReceptorsIBA
06/2003
1Codon (Codons)IBA
06/2003
1TransferasesIBA
06/2003
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
06/2003
1CitalopramFDA LinkGeneric
06/2003
1catechol (pyrocatechol)IBA
06/2003
1Interleukin-6 (Interleukin 6)IBA
10/2002

Therapy/Procedure

12Phototherapy (Light Therapy)
01/2016 - 10/2003
5Therapeutics
06/2014 - 09/2004
4Injections
08/2013 - 04/2010
2Transcranial Magnetic Stimulation
12/2014 - 01/2009
2Secondary Prevention
08/2013 - 11/2010